Innovation, sustainability and society
Welcome to the
Campopiano Group
Based in the School of Chemistry at the University of Edinburgh (King's Buildings), our group combines synthetic chemistry, protein chemistry, and microbiology to study important proteins, enzymes, and natural products from both mammals and bacteria. We specialize in cloning and over-expressing target genes to examine the proteins they encode, and we use advanced techniques to analyze their structures and mechanisms.
Research
Biocatalysis
Inspired from the nature product biosynthesis pathways, we studies the biocatalysts' native functions to build relavent cascades. By introducing appropriate substrate/biocatalyst architecture engineering we introduce new-to-nature cryptic catalytic functions
Natural Product Biosynthesis
We study how bacteria, mammals, and yeast produce sphingolipids, essential components of cell membranes that play critical roles in metabolism.
Protein Drug Targets
We study protein targets involved in essential metabolic reactions, including drug detoxification, metal uptake, and vitamin-dependent modifications, such as GSTs, FBPs, and BPLs.
Publications
About us
The Campopiano Group at the University of Edinburgh investigates essential proteins and enzymes using synthetic chemistry, protein chemistry, and microbiology. By enhancing enzyme stability and activity, we contribute to eco-friendly catalysts for pharmaceuticals and sustainable chemical production.
